Diễn viên chính：William Shatner, Leonard Nimoy, DeForest Kelley, James Doohan, George Takei, Walter Koenig, Nichelle Nichols, Christopher Plummer, Mark Lenard, David Warner, Kim Cattrall, Rosanna DeSoto, Kurtwood Smith, Brock Peters, Paul Rossilli, John Schuck, Iman, Leo